| FIRST-LINE ANTIBIOTIC TREATMENT FOR BRD
Q. What is a “first-line” BRD treatment?
A. The initiation of the treatment regimen for symptomatic cattle – cattle with clinical signs of BRD.
Q. What is the objective of a first-line treatment?
A. To stop the progress of the infection and prevent animals who show signs of BRD from becoming so sick they are rendered
unproductive or die. This involves identifying sick cattle at the earliest possible stage – a highly-refined and valuable skill in a
large feedlot, where a pen rider may be overseeing tens of thousands of animals each day.
Q. What are the criteria for an effective antibiotic in a stocker operation?
A. Speed, broad-spectrum power, and length of control are critical, especially if treated cattle are not held in a hospital
pen and must be rounded up on pasture for a re-pull treatment. Of course, it must also be cost-effective.
Q. What is the advantage of flexible dosage?
A. Certain antibiotics allow you the flexibility of increasing dosage and the confidence that you are still working within
the approved label. For example, TETRADURE 300 gives you a dosage range that lets you increase the antibiotic power by as much as 50%
(9.0 to 13.6 mg/lb. bodyweight), so you can more effectively match the antibiotic strength to the severity of the infection.
Q. What is the spectrum of TETRADURE 300?
A. TETRADURE 300 is effective against all three of the major causes of BRD Mannheimia (Pasteurella) haemolytica,
Pasteurella multocida, and Haemophilus somnus. It is also an excellent treatment for pinkeye (Moraxella bovis), and footrot
associated with Fusobacterium necrophorum (see TETRADURE 300 label for special dosage and administration instructions for footrot).
Q. Does TETRADURE 300 work fast? How long does it last?
A. TETRADURE 300 reaches therapeutic serum levels within an hour. It has a unique long-acting composition and carrier and
maintains therapeutic levels for 7 to 8 days at 13.6 mg/lb.
Q. How effective is TETRADURE 300 at reaching affected lung tissue?
A. In trials, using an oxytetracycline, such as Tetradure 300, the product effectively reached the infected lung tissue.5
Q. What is the pre-slaughter withdrawal for TETRADURE 300?
A. At the recommended 9.0 mg/lb. to 13.6 mg/lb. bodyweight, TETRADURE 300 should not be administered within 28 days of
slaughter. This is fairly typical of first-line treatments, and should not interfere with routine management if good diagnostic techniques
are used. TETRADURE 300 may not be the best choice as a “rescue” treatment where the animal’s chances of survival are very
low and you want to keep salvage options open.
Q. Can TETRADURE 300 be used in lactating dairy cows?
A. No, TETRADURE 300 is for use only on beef cattle or non-lactating dairy cows, calves or bulls with clinical signs of
pneumonia, BRD, or in cases of bacterial enteritis caused by E. coli.
Q. Has TETRADURE 300 been tested against other leading products?
A. TETRADURE 300 has shown itself to be unsurpassed for efficacy and value. A recent trial compared TETRADURE 300 with
Nuflor® and Liquamycin® LA-200® (oxytetracycline) on feeder cattle showing signs of BRD. In this trial, a single treatment of
TETRADURE 300 was twice as effective as LA-200 in reducing mortality rates, and statistically comparable to two treatments of the much more
expensive Nuflor. Trials have also compared TETRADURE 300 to the premium-priced Micotil® as a metaphylactic treatment and delivered similar
results in mortality, re-pull rates, and rate of gain.6
Click here for more information about TETRADURE 300 or for a TETRADURE product label.
Legals: ®Merial is a registered trademark of Merial.
™TETRADURE is a trademark of Merial.
®Nuflor is a registered trademark of Schering Plough Veterinary Corp.
®Liquamycin and LA-200 are registered trademarks of Pfizer Inc.
®Micotil is a registered trademark of Elanco Animal Health.
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Ed Drung, Feedyard Operator, Columbus, Neb.
